Sappington’s Theory & Treatment of Fevers

As I have long since departed from the the­ory and prac­tice in which I was prin­ci­pally taught, and am now engaged in writ­ing against them, it may be proper that I should give my rea­sons to the pub­lic for doing so.  —John Sap­ping­ton, The­ory and Treat­ment of Fevers.

The library has recently acquired one of the ear­li­est books pub­lished west of the Mis­sis­sippi and the first med­ical book printed in Mis­souri, John Sappington’s The­ory and Treat­ment of Fevers … Revised and cor­rected by Fer­di­nand Stith, Arrow Rock [Mo.], Pub­lished by the Author, 1844.

The book, Sappington’s first and pub­lished by the author in aproximatey16,000 copies, went against con­tem­po­rary med­ical treat­ment of fevers, which included blood­let­ting, vom­it­ing with the use of emet­ics, and admin­is­ter­ing Calomel or Mer­cury Chlo­ride as a purga­tive, and instead advo­cated the effi­cacy of his own anti-fever pills. Sap­ping­ton had found both med­ical and com­mer­cial suc­cess in fight­ing fevers with the release of his “Dr. Sappington’s Anti-Fever Pills,” which he began to sell in 1832. The ingre­di­ent respon­si­ble for their effi­cacy was qui­nine, a sub­stance derived from the bark of a South Amer­i­can tree. It was soon dis­cov­ered that the pills were highly effec­tive in the treat­ment of malaria (a dreaded and wide-spread dis­ease for south­ern fron­tier set­tlers), and in 1835, Sap­ping­ton founded Sap­ping­ton and Sons to meet demand and widen dis­tri­b­u­tion.  The The­ory and Treat­ment of Fevers, how­ever, was not a com­mer­cial or adver­tise­ment ploy to sell more pills, which Sap­ping­ton had been suc­cess­fully sell­ing for nearly a decade by the time of the book’s pub­li­ca­tion. Rather, the author pro­fessed a benev­o­lent desire and pur­pose for the book and even went so far as to included the ingre­di­ents for his lucra­tive anti-fever pills:

Although the author has vended pills to a large amount, and real­ized con­sid­er­able sums of money by his sales, the peo­ple have also saved a great many dol­lars by using them; been relieved of much pain and suf­fer­ing, and very many lives have no doubt been saved and pro­longed. The author con­sid­ers him­self dri­ven to this alter­na­tive, more from motives of benev­o­lence than from those of self-interest. (79)

Sappington’s Anti-Fever Pills “were sim­ply com­posed of one grain qui­nine each, three-fourths of a grain of liquorice, and one-fourth grain of myrrh, to which was added just so much of the oil of sas­safras as would give to them an agree­able odor” (79).

Princeton’s copy con­tains the book­plate of H. P. Engle, M. D., undoubt­edly the county physi­cian Harry P. Engle of New­ton, Iowa:

A bio­graph­i­cal sketch and pho­to­graph of H. P. Engle, M. D., can be found in the Stan­dard His­tor­i­cal Atlas of Jasper County, Iowa, while Dr. Engle’s early adop­tion of the auto­mo­bile and its ben­e­fit to county physi­cians can be read in “The Most Sat­is­fac­tory Invest­ment for the County Physi­cian Harry P. Engle, M.D. New­ton, Iowa.”

The Sap­ping­tons went on to became a very promi­nent and influ­en­tial Mis­souri fam­ily.  A detailed account of Dr. Sappington’s life and his legacy, includ­ing por­traits of fam­ily mem­bers and pho­tographs of his Anti-Fever Pills and related ephemera, can be found on the State His­tor­i­cal Soci­ety of Missouri’s His­toric Mis­souri­ans, Nurses & Doc­tors, web­site: John S. Sap­ping­ton (1776–1856). The his­tor­i­cal soci­ety also houses the Sap­ping­ton Fam­ily Papers.

Select Bib­li­og­ra­phy:

Eimas, Richard (Ed.). Heirs of Hip­pocrates: The Devel­op­ment of Med­i­cine in a Cat­a­logue of His­toric Books in the Hardin Library for the Health Sci­ences, the Uni­ver­sity of Iowa. Third Edi­tion. Iowa City: Pub­lished for the Uni­ver­sity of Iowa Libraries by the Uni­ver­sity of Iowa Press, 1990. Avail­able online: Heirs of Hip­pocrates.

Mor­row, Lynn. “Dr. John Sap­ping­ton: South­ern Patri­arch in the New West.” Mis­souri His­tor­i­cal Review. Vol 90, no. 1 (Octo­ber 1995): 38–60.

Sap­ping­ton, John. The­ory and Treat­ment of Fevers … Revised and cor­rected by Fer­di­nand Stith.  Arrow Rock [Mo.]: Pub­lished by the Author, 1844.