"Springer is pleased to announce the publication of the 500th volume in the best-selling series, Methods in Molecular Biology. To commemorate this milestone, we have made some protocols from this 500th volume – Systems Biology, edited by Ivan Maly – available for free online at SpringerProtocols.com. As this new volume demonstrates, Springer continues to publish protocols at the cutting-edge of research."
From an email ad from the publisher, 4/23/09.

PUL has an ongoing subscription to this Springer series.  We’ve not yet received volume 500 — but we have received #528. (They often come out of sequence.)  You may want to follow their link.  They have ways to store your own protocols, and videos of some, and links to the newest with RSS feeds…similar to Wiley’s offerings.