Category Archives: Chemistry

CRISPR — HOW IT WORKS, an animation from HHMI

Posted on by

Summary

Explore this dynamic interactive to learn the basic principles of how this revolutionary tool works and the many ways in which scientists are using it in their research.

Start Click & Learn

Since it was first described in 2012, CRISPR-Cas9 (often shortened to “CRISPR”) has generated much interest both for its exciting potential for treating genetic disease and potential ethical and safety concerns, such as by creating “designer babies” or “superhumans.” So far, CRISPR-based technologies are having the biggest impact in research laboratories where they are applied to a broad range of biological studies. These technologies are relatively cheap, easy to use, and allow researchers to ask new questions and get results faster than previously possible.

The CRISPR-Cas9: Mechanism & Applications interactive allows students to explore and learn about a biotechnology tool that is at the forefront of scientific research and hear directly from leading researchers about how they use CRISPR. It consists of a self-paced interactive animation and a series of short videos of different scientists who are using CRISPR-Cas9 technologies for basic research, medical, and agricultural applications.

In addition to the interactive, we’ve compiled a set of images, animations, and GIFs for use on social media, in the classroom, and for presentations to the public. Please credit HHMI BioInteractive when you use them.

Source: The BioInteractive Team <biointeractive@hhmi.org>

Data Management Plan Presentation – Wed., March 28th

Posted on by

Data Management Plan Presentation

Wednesday, March 28, 12:00 – 1:00 pm

347 Lewis Science Library, Washington Road & Ivy Lane
[Lunch will be provided. RSVP here.]

This one-hour presentation by PU librarians, OIT and PICSciE/Research Computing staff is open to Princeton researchers, graduate students and grants personnel. Please share with those who may benefit from this presentation.

Topics

  • Why manage research data?
  • Elements of data management
  • How to write a data management plan
  • Common data management issues
  • Best practices for managing research data
  • Resources and support on campus

National Service Center for Environmental Publications

Posted on by

https://www.epa.gov/nscep
EPA Publications
“You can search, retrieve, download, print, and order EPA technical, scientific, and educational materials from this site – all free of charge!”
LAST UPDATED ON JANUARY 9, 2018

Chemists to get their own preprint server

Posted on by

World’s largest scientific society plans to introduce ChemRxiv for a traditionally reluctant discipline.

  • Daniel Cressey

11 August 2016

Nature DOI: doi:10.1038/nature.2016.20409

http://www.nature.com./news/chemists-to-get-their-own-preprint-server-1.20409

From Bob Buntrock (Princeton Class of ??)   on the CHMINF Listserv.

Like arXiv and bioRxiv, ChemRxiv, hopes to facilitate the discovery and sharing of significant happenings in Chemistry.  ACS is welcoming input during this planning stage.

PubMed is 20 Years Old

Posted on by

PubMed Celebrates its 20th Anniversary! | NLM in Focus

PubMed logo next to lit birthday candles in the shape of the number twentyPubMed was first released two decades ago in January 1996 as an experimental database under the National Center for Biotechnology Information (NCBI) retrieval system. The word “experimental” was dropped from the website in April 1997, and on June 26, 1997, a Capitol Hill press conference officially announced free MEDLINE access via PubMed.More information, a brief history can be found here:

https://infocus.nlm.nih.gov/2016/06/30/pubmed-celebrates-its-20th-anniversary

PubMed Celebrates its 20th Anniversary! | NLM in Focus

“PubMed hit the milestone of 26 million citations; over one million citations are added every year.”

 

 

VIRTUAL TEXTBOOK OF ORGANIC CHEMISTRY

Posted on by
Virtual Textbook of Organic Chemistry  
www2.chemistry.msu.edu/faculty/reusch/VirtTxtJml/intro1.htm
William H. Reusch, emeritus professor at Michigan State University, published his Introduction to Organic Chemistry in 1977. Readers may purchase it for a list price of $137.74; or they may access the Virtual Textbook of Organic Chemistry, which contains nearly the same information online, for free, on this surprisingly comprehensive website. Here readers will find a fully operational organic chemistry textbook, divided into the two overarching topics of General Principles and Functional Group Reactions. Within General Principles, readers will learn the basics of Structure & Bonding, Intermolecular Forces, Chemical Reactivity, Aromaticity, and other subjects. Functional Group Reactions covers Alkanes, Alkenes, Alkynes, Alcohols, and many other subjects. For readers looking for a comprehensive, freely available organic chemistry textbook, this site will be a true boon. [CNH]”

Source:  The Scout Report, Univ. of Wisconsin, Jan. 22, 2016

Table of Contents

 

MEDLINE ANNUAL CHANGES/UPDATES

Posted on by

National Library of Medicine Technical Bulletin

This article collects the notable data changes made to MEDLINE during annual National Library of Medicine (NLM) maintenance known as Year-End Processing (YEP) for 2016:

MEDLINE Data Changes — 2016

Tybaert S. NLM Tech Bull. 2015 Nov-Dec;(407):e8.

2015 December 08 [posted]

Brand new concepts include: Autism Spectrum Disorder, Human Embryonic Stem Cells, Olive Oil, Origin of Life, Open Access Publishing, War-Related Injuries, RNAi Therapeutics, and many more terms.  Medline thesaurus terms are remapped when changes occur, so as to include articles under former headings.

Medical Subject Headings for 2016 are now available online

Posted on by

NLM [National Library of Medicine] New files for Nov 10, 2015

*NLM Technical Bulletin, Nov-Dec 2015, 2016 Medical Subject Headings Available for Download  http://www.nlm.nih.gov/pubs/techbull/nd15/nd15_2016_mesh_avail.html

NLM Technical Bulletin, Sep-Oct 2015, 2016 MeSH Headings Available in the MeSH Browser [Editor’s note added November 10, 2015]  http://www.nlm.nih.gov/pubs/techbull/so15/so15_2016_mesh_browser.html

The Cambridge Structural Database has reached no. 800,000

Posted on by

“The Cambridge Crystallographic Data Centre is delighted to announce that there are now over 800,000 entries in the Cambridge Structural Database. The 800,000th entry is a copper-containing metal-organic crystal structure determined by researchers in Spain and published in Crystal Growth & Design.

You can read more about this structure and the significance of this milestone at http://www.ccdc.cam.ac.uk/NewsandEvents/News/Pages/NewsItem.aspx?newsid=42 and in our blog post at http://www.ccdc.cam.ac.uk/Community/Blog/pages/BlogPost.aspx?bpid=58.

We take this opportunity to express our appreciation for the immense contribution made by researchers past and present to the continuing growth and success of the Cambridge Structural Database.”

As reported to the CHMINF-L on Oct. 23, 2015, by

Dr Ian Bruno: Director, Strategic Partnerships

The Cambridge Crystallographic Data Centre (CCDC)

Tel: +44-1223-336013   Email: bruno@ccdc.cam.ac.uk

Virtual Cell Animation Collection

Posted on by

This website is hosted by North Dakota State University, the Molecular & Cellular Biology Learning Center:

http://vcell.ndsu.nodak.edu/animations

There are 6 videos on molecular processes, 9 on cellular processes and 9 on cellular energy conversions.   There is also an overview video.  Sponsors include the National Science Foundation and the U.S. Dept. of Education.

Source:  Choice, Sept. 2015, p. 34, listing of “Outstanding Academic Websites of 2014”