Category Archives: Genetics

CRISPR — HOW IT WORKS, an animation from HHMI

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Summary

Explore this dynamic interactive to learn the basic principles of how this revolutionary tool works and the many ways in which scientists are using it in their research.

Start Click & Learn

Since it was first described in 2012, CRISPR-Cas9 (often shortened to “CRISPR”) has generated much interest both for its exciting potential for treating genetic disease and potential ethical and safety concerns, such as by creating “designer babies” or “superhumans.” So far, CRISPR-based technologies are having the biggest impact in research laboratories where they are applied to a broad range of biological studies. These technologies are relatively cheap, easy to use, and allow researchers to ask new questions and get results faster than previously possible.

The CRISPR-Cas9: Mechanism & Applications interactive allows students to explore and learn about a biotechnology tool that is at the forefront of scientific research and hear directly from leading researchers about how they use CRISPR. It consists of a self-paced interactive animation and a series of short videos of different scientists who are using CRISPR-Cas9 technologies for basic research, medical, and agricultural applications.

In addition to the interactive, we’ve compiled a set of images, animations, and GIFs for use on social media, in the classroom, and for presentations to the public. Please credit HHMI BioInteractive when you use them.

Source: The BioInteractive Team <biointeractive@hhmi.org>

Data Management Plan Presentation – Wed., March 28th

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Data Management Plan Presentation

Wednesday, March 28, 12:00 – 1:00 pm

347 Lewis Science Library, Washington Road & Ivy Lane
[Lunch will be provided. RSVP here.]

This one-hour presentation by PU librarians, OIT and PICSciE/Research Computing staff is open to Princeton researchers, graduate students and grants personnel. Please share with those who may benefit from this presentation.

Topics

  • Why manage research data?
  • Elements of data management
  • How to write a data management plan
  • Common data management issues
  • Best practices for managing research data
  • Resources and support on campus

Best of the Web, GEN (Vol. 37, No. 8) SciPy PYTHON

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“Computer programming is becoming (or rather, already has become) an essential skill for modern-day life scientists. A popular programming language in many fields is Python, in large part due to its open-source development. As a result, there exist many free resources available to both experienced and novice Python users. A large collection of such resources can be found on SciPy.org, home of a number of scientific and computational software packages/libraries for Python. In addition to offering free downloads of those packages, the SciPy website also includes SciPy Central (a collection of useful Python code snippets), a blog, documentation for the various software packages, and a place for users to report bugs. Site visitors in search of even more information can browse the SciPy Cookbook, a collection of user-contributed “recipes” that span topics such as graphics, linear algebra, simple plotting, and differential equations.”

Genetic Engineering & Biotechnology News, April 15, 2017,  URL:scipy.org

Rated “Excellent”, free software downloads, good documentation

Viral Zone Best of the Web, Genetic Engng & Biotech News

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BestWeb_ViralZoneSource: | Best of the Web | GEN ViralZone |

Genetic Engineering & Biotechnology News//

Jun 15, 2016 (Vol. 36, No. 12)

“Do you know your DNA viruses from your RNA viruses, and can you spot a retrotranscribing virus when you see one? If not, the ViralZone from the Swiss Institute of Bioinformatics is a fantastic web resource for virologists and other scientists who use viral tools in their research. ViralZone includes description pages for over 500 viruses, and site visitors can access these pages either by a targeted search for a specific virus or by browsing the virus pages by a virus’ Baltimore classification, host, or virion. The website also includes a great deal of general information about viral molecular biology, including topics such as virus entry/exit, replication, and genome evolution. On the homepage, site visitors will find a news section (including a weekly podcast) so that they can keep up to date on the latest viral happenings.”

 

 

MEDLINE ANNUAL CHANGES/UPDATES

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National Library of Medicine Technical Bulletin

This article collects the notable data changes made to MEDLINE during annual National Library of Medicine (NLM) maintenance known as Year-End Processing (YEP) for 2016:

MEDLINE Data Changes — 2016

Tybaert S. NLM Tech Bull. 2015 Nov-Dec;(407):e8.

2015 December 08 [posted]

Brand new concepts include: Autism Spectrum Disorder, Human Embryonic Stem Cells, Olive Oil, Origin of Life, Open Access Publishing, War-Related Injuries, RNAi Therapeutics, and many more terms.  Medline thesaurus terms are remapped when changes occur, so as to include articles under former headings.

Medical Subject Headings for 2016 are now available online

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NLM [National Library of Medicine] New files for Nov 10, 2015

*NLM Technical Bulletin, Nov-Dec 2015, 2016 Medical Subject Headings Available for Download  http://www.nlm.nih.gov/pubs/techbull/nd15/nd15_2016_mesh_avail.html

NLM Technical Bulletin, Sep-Oct 2015, 2016 MeSH Headings Available in the MeSH Browser [Editor’s note added November 10, 2015]  http://www.nlm.nih.gov/pubs/techbull/so15/so15_2016_mesh_browser.html

Directory of Open Access Journals — DOAJ

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This directory of OA journals is hosted by Lund University Libraries in Sweden.  From their homepage: http://www.doaj.org:

“DOAJ is an online directory that indexes and provides access to high quality, open access, peer-reviewed journals.”   One can search by keywords or browse through broader and narrower subject headings.

These stats are from their website, accessed Sept. 28, 2015:

  • 10,569 Journals
  • 6,464 searchable at Article level
  • 134 Countries
  • 2,091,552 Articles

Seen in “Outstanding Websites of 2014”, Choice, Sept. 2015, p. 33

ProQuest full text of scholarly journal content soon indexed by Google Scholar

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By Kurt Sanford, CEO

“ProQuest is enabling the full text of its scholarly journal content to be indexed in Google Scholar, improving discovery and research outcomes. Our goal is that by the third quarter of 2015, users starting their research in Google Scholar will be able to access full text via ProQuest.”

http://www.proquest.com/blog/pqblog/2015/Why-ProQuest-is-working-with-Google.html

Feed

Tuesday, 18th August 2015

ProQuest Scholarly Content Now Discoverable in Google Scholar

By Africa S. Hands

From No Shelf Required:

ProQuest has marked another milestone in ease of access to its rich research content. The full text of its scholarly content – including journals and working papers – is now indexed in Google Scholar, enabling Google Scholar users to seamlessly discover and access their library’s ProQuest collections. Efficiency and productivity for both ProQuest and Google Scholar users is improved, while libraries benefit from increased usage for their subscribed collections.

Full story >>

http://www.libraries.wright.edu/noshelfrequired/2015/08/12/proquest-scholarly-content-now-discoverable-in-google-scholar/

Source via: ResourceShelf Newsletter – 8th September 2015

[ResourceShelf] Newsletter 643

BioOne — adding 7 titles, but after 12/2015 ceasing to contain Entomological Soc. of Am. & Am. Soc. of Mammalogists publications

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” BioOne adds seven new journals to BioOne Complete – 04 Sep 2015

BioOne, a nonprofit publisher that aims to make scientific research more accessible, has added seven new journals to BioOne Complete, its online aggregation of independently-published, subscribed and open-access titles.

Joining the subscribed aggregation in January 2016 will be: Caribbean Journal of Science, published by the University of Puerto Rico at Mayagüez; Journal of Entomological Science, published by the Georgia Entomological Society; Journal of the Lepidopterists’ Society, published by The Lepidopterists’ Society; and Systematic and Applied Acarology, published by the Systematic and Applied Acarology Society (UK). Joining BioOne Complete as open-access participants will be: Paleontological Contributions, published by The Paleontological Institute at The University of Kansas; and Palaeodiversity and Stuttgarter Beiträge zur Naturkunde A, both published by The Stuttgart State Museum of Natural History, Germany.

These titles represent a wealth of content in biodiversity conservation, entomology, paleontology, and natural history. Their collective backfile encompasses 48 years and over 12,000 new pages for BioOne Complete. In 2016, the aggregation will be home to 191 publications (130 current, 43 backfile-only, and 18 open-access titles), comprising over 1.2 million pages and growing daily. 78% of BioOne Complete’s subscribed titles are ranked in Thomson Reuters’ Journal Citation Reports, and 25% are based outside of the US. Furthermore, 73% of current titles are available in full-text XML exclusively through BioOne Complete.

Just as these new additions enhance a subscription to BioOne Complete, BioOne participation represents a key step forward for each of these nonprofit publishers to make their content more accessible to a global audience.

As of December 31, 2015, the publications of the Entomological Society of America and the American Society of Mammalogists will cease adding new content to BioOne Complete. In accordance with BioOne’s commitment to perpetual access, all previously deposited issues from 2000-2015 (sixteen years of content), will remain accessible to BioOne Complete subscribers in perpetuity.”

Source:  Knowledgespeak Newsletter, 9/4/2015

Conversations in Genetics History

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Oral History of Genetics Now Available Online

“The Genetics Society of America (GSA) and Executive Producer Rochelle Easton Esposito, PhD, are pleased to announce that Conversations in Genetics, an oral history of our intellectual heritage in genetics, is now available for free online viewing at http://www.genestory.org/.”

Source:  Newswise SciWire for 30-Apr-2015

Other interviewees to come:  King, Cavalli-Sforza, Meyerowitz, Horowitz