Chemical Abstracts Service (CAS), the world’s authority for chemical information, has registered the 100 millionth chemical substance in the CAS REGISTRY, in the 50th anniversary year of the world’s largest database of unique chemical substances.

With a steady increase in patenting activity around the globe, it is not surprising the 100 millionth small molecule registration comes from a patent. In this case, the substance was reported in a World Intellectual Property Organization (WIPO) patent from Coferon, Inc. (Coferon) in Stony Brook, NY. The inventors claim the molecule, CAS RN 1786400-23-4, available in both SciFinder® and STN®, is a novel therapeutic designed to treat acute myeloid leukemia.

Started in 1965 as a project to uniquely identify and track chemical substance information, the CAS Registry system is the only complete and accurate source of unique identifiers, known as CAS Registry Numbers for all organic and inorganic substances disclosed in scientific publications and other reputable sources. Today, scientists, intellectual property professionals and compliance specialists around the world rely on CAS Registry Numbers to instantaneously identify and access the exact chemical needed for their research, safety and compliance needs.

The invention of CAS REGISTRY revolutionized the chemical information field and transformed research since the mid 60’s, and CAS Registry Numbers are ubiquitous in mainstream society today. Global regulatory organisations, including the United States Environmental Protection Agency and The ACT on the Registration and Evaluation of Chemicals regulatory body in Korea, require all new chemical substances manufactured or imported to be identified by a CAS Registry Number. These are also used on Materials Safety Data Sheets (MSDS) around the world as a reliable resource for safe handling and transport of chemicals. CAS Registry Numbers are found on consumer products we use, e.g., paint cans and shampoo labels, and are relied upon in numerous web information sources, including chemical suppliers sites, Wikipedia, PubChem, and ChemSpider, to provide the one unique key that can open the world of information about that substance.

The substantial growth in worldwide chemical discoveries over the past 10 years is reflected in CAS REGISTRY. A view of all substances added since 1965 shows that the pace of research has significantly accelerated in the past ten years. Of the 100 million substances in CAS REGISTRY, approximately 75 million were added over the past 10 years. On average, CAS has registered 1 substance every 2.5 minutes over the past 50 years.
Source:  Knowledgespeak Newsletter 6/30/2015