ToxCastDB – bioassays for potential human toxicity

ToxCastDB, from the US Environmental Protection Agency. Internet Resource. Reviewed in 2011dec CHOICE. p. 652
http://actor.epa.gov/actor/faces/ToxCastDB/Home.jsp

[Visited Sep’11] ToxCastDB provides public access to data gathered by the ToxCast project that screens chemicals for potential human toxicity using more than 500 high-throughput screening bioassays from nine bioassay vendors. ToxCast is part of the EPA’s National Center for Computational Toxicology. As the Basic Info link states, ToxCast links “biological, metabolic and cellular pathway data to gene and in vitro assay data for the chemicals screened.” At the time of this review, 300 chemicals had been screened, with another 700 projected by the end of 2012.”

To read the whole review: http://www.cro2.org/default.aspx?page=search_results

Student Design Competition for Sustainability (EPA)

From the Green Chemistry Program electronic newsletter:

P3: People, Prosperity and the Planet: Student Design Competition for Sustainability

Solicitation Open: Sept 23, 2009 – Dec 23, 2009

  • EPA is seeking applications to research, develop, and design solutions to real world challenges involving the overall sustainability of human society.
  • Applications can address any of these research areas: Agriculture, Materials and Chemicals, Energy Information Technology, Water, & Built Environment.
  • The P3 Award Program is open to degree-granting public & private institutions of higher education located in the U.S.

See the P3 website at: www.epa.gov/P3 for more details about the program & a link to the solicitation.

Environmental Chemistry Information System (ECIS)

Trial subscriptions to Environmental Chemistry Information System are free during the month of September. Check http://www.nisc.com for details. These databases are nearly all separate flles on government websites. There are over 8 million records for nearly 700,000 chemicals.

Should we suscribe?

The ECIS News (Newsletter Archive)

A wealth of information about chemicals in the environment.

  1. Chemical/Physical properties
    OBSERVATIONS, SANSS
  2. Biodegradation/Bioremediation
    BIODEG, BIOLOG
  3. Site Assessment
    BRS, CERCLIS, FINDS, ICIS (DOCKET),RCRIS, TRI (1987-2005)
  4. Toxicity & Carcinogenicity
    AQUIRE, CCRIS, CRISP, EMIC, GIABS, GENE-TOX, IRIS, MEDLINE Subset, NIOSHTIC
    Subset, RTECS, TERRETOX, TSCATS
  5. Regulations
    TSCAINV, TSCAPP
  6. HAZMAT
    CHRIS, HSDB, MALLIN, New Jersey Hazardous Substance Factsheets, OHMTADS

Some of the databases are included in the TOXSEEK cluster provided by the U.S. government and listed in our “Articles and Databases” listing.

Environmental Health & Toxicology Portal

The U.S. government, National Library of Medicine, National Institutes of Health, Specialized Information Services more specifically, has set up an Environmental Health & Toxicology portal to web-based information about Chemicals and Drugs, Diseases and the Environment, Environmental Health, Occupational Safety and Health, Poisoning, Risk Asessment and Regulations, Toxicology and Pesticide Exposure.

Information geared to researchers and students may be specified…as well as the public or schools.