[Visited Sep’11] ToxCastDB provides public access to data gathered by the ToxCast project that screens chemicals for potential human toxicity using more than 500 high-throughput screening bioassays from nine bioassay vendors. ToxCast is part of the EPA’s National Center for Computational Toxicology. As the Basic Info link states, ToxCast links “biological, metabolic and cellular pathway data to gene and in vitro assay data for the chemicals screened.” At the time of this review, 300 chemicals had been screened, with another 700 projected by the end of 2012.”
NLM® Resource Update: Crude Oil and Dispersants Added to the Hazardous Substances Data Bank
[Editor’s Note: This is a reprint of an announcement published on NLM-Tox-Enviro-Health-L, an e-mail announcement list available from the NLM Division of Specialized Information Services. To subscribe to this list, please see the NLM-TOX-ENVIRO-HEALTH-L Join, Leave, or Change Options page.]
The National Library of Medicine® (NLM) Division of Specialized Information Services has added crude oil and dispersant records to the Hazardous Substances Data Bank (HSDB®).
In response to the 2010 Deep Water Horizon oil spill, the HSDB development team and the HSDB Scientific Review Panel (SRP) compiled and reviewed data for crude oil, Corexit 9500, and Corexit 9527 records. Although many dispersants exist, the two selected were most widely used during recent oil clean up efforts in the United States Gulf area and are on the U.S. Environmental Protection Agency (EPA) list of authorized dispersants for use on the National Contingency Plan (NCP) Product Schedule.
The HSDB records include data on human health effects, animal toxicity studies, environmental fate and exposure, and hazard information.
“The U.S. Environmental Protection Agency (EPA) released a new database called ToxRefDB, which allows scientists and the public to search and download thousands of toxicity testing results on hundreds of chemicals. ToxRefDB captures 30 years and $2 billion of testing results. It provides detailed chemical toxicity data in an accessible format. It is a part of ACToR (Aggregated Computational Toxicology Resource), an online data warehouse that collects data from about 500 public sources on tens of thousands of environmentally relevant chemicals http://actor.epa.gov/toxrefdb/faces/Home.jsp.”
ToxLearn is a multi-module online learning tool that provides an introduction to toxicology. It can be used as an ancillary curriculum to a first-level undergraduate toxicology course, and can provide users of NLM’s toxicology databases with a working knowledge of basic toxicology principles. ToxLearn modules will be made available as they are completed. Module 1 covers “Toxicology and Dose Response.”
September 9, 2009: Toxipedia.org, in partnership with the USA National Library of Medicine (NLM), the International Union of Toxicology (IUTOX), and the Institute of Neurotoxicology and Neurological Disorders (INND), announces the launch of the World Library of Toxicology, Chemical Safety, and Environmental Health, briefly referred to as the World Library of Toxicology (WLT) (http://www.wltox.org).
This free global Web portal provides the scientific community and public with links to major government agencies, non-governmental organizations, universities, professional societies, and other groups addressing issues related to toxicology, public health, and environmental health.
Trial subscriptions to Environmental Chemistry Information System are free during the month of September. Check http://www.nisc.com for details. These databases are nearly all separate flles on government websites. There are over 8 million records for nearly 700,000 chemicals.
Should we suscribe?
The ECIS News (Newsletter Archive)
A wealth of information about chemicals in the environment.
BRS, CERCLIS, FINDS, ICIS (DOCKET),RCRIS, TRI (1987-2005)
The U.S. government, National Library of Medicine, National Institutes of Health, Specialized Information Services more specifically, has set up an Environmental Health & Toxicology portal to web-based information about Chemicals and Drugs, Diseases and the Environment, Environmental Health, Occupational Safety and Health, Poisoning, Risk Asessment and Regulations, Toxicology and Pesticide Exposure.
Information geared to researchers and students may be specified…as well as the public or schools.