Cancer cells exchange leaders during invasion (PNAS)

By Catherine Zandonella, Office of the Dean for Research A new study has found that cancer cells appear to exchange leading roles as they migrate out of a tumor in the early stages of invasion, or metastasis, of other sites in the body. Metastatic cancer accounts for more than 90% of cancer-related deaths. A team … Continue reading Cancer cells exchange leaders during invasion (PNAS)

The role of breast structure in tumor development (PNAS)

Why do some breast tumors grow aggressively while others grow slowly? In this study, researchers found that the stiffness of the cells in the area around an emerging tumor influences its ability to grow and invade the breast. Using a 3-D fabrication process, the researchers created artificial breast ducts containing normal breast cells and a … Continue reading The role of breast structure in tumor development (PNAS)