Genetically engineered mice could boost fight against aggressive hepatitis

Article provided by the Department of Molecular Biology Hepatitis delta virus (HDV) causes the most aggressive form of viral hepatitis in humans, putting at least 20 million people worldwide at risk of developing liver fibrosis, cirrhosis, and liver cancer. Efforts to develop effective treatments against HDV have been hampered by the fact that laboratory mice … Continue reading Genetically engineered mice could boost fight against aggressive hepatitis

Princeton researchers report new system to study chronic hepatitis B

By the Department of Molecular Biology Scientists from Princeton University's Department of Molecular Biology have successfully tested a cell-culture system that will allow researchers to perform laboratory-based studies of long-term hepatitis B virus (HBV) infections. The technique, which is described in a paper published July 25 in the journal Nature Communications, will aid the study … Continue reading Princeton researchers report new system to study chronic hepatitis B

New mouse model for hepatitis C (Nature)

By Catherine Zandonella, Office of the Dean for Research Hepatitis C affects about three million people in the U.S. and is a leading cause of chronic liver disease, so creating a vaccine and new treatments is an important public health goal. Most research to date has been done in chimpanzees because they are one of … Continue reading New mouse model for hepatitis C (Nature)