Genetically engineered mice could boost fight against aggressive hepatitis

Article provided by the Department of Molecular Biology Hepatitis delta virus (HDV) causes the most aggressive form of viral hepatitis in humans, putting at least 20 million people worldwide at risk of developing liver fibrosis, cirrhosis, and liver cancer. Efforts to develop effective treatments against HDV have been hampered by the fact that laboratory mice … Continue reading Genetically engineered mice could boost fight against aggressive hepatitis

Researchers find an alternative mode of bacterial quorum sensing

By the Department of Molecular Biology Whether growing in a puddle of dirty water or inside the human body, large groups of bacteria must coordinate their behavior to perform essential tasks that they would not be able to carry out individually. Bacteria achieve this coordination through a process called quorum sensing in which the microorganisms … Continue reading Researchers find an alternative mode of bacterial quorum sensing

An immune signaling pathway for control of Yellow Fever Virus infection

By the Department of Molecular Biology Princeton University researchers have uncovered a critical role for a new immune signaling pathway in controlling infection by the flavivirus Yellow Fever Virus (YFV).  The paper describing this discovery was published today in the journal mBio. Infection with YFV causes a devastating illness with a mortality rate of up … Continue reading An immune signaling pathway for control of Yellow Fever Virus infection