Researchers find an alternative mode of bacterial quorum sensing

By the Department of Molecular Biology Whether growing in a puddle of dirty water or inside the human body, large groups of bacteria must coordinate their behavior to perform essential tasks that they would not be able to carry out individually. Bacteria achieve this coordination through a process called quorum sensing in which the microorganisms … Continue reading Researchers find an alternative mode of bacterial quorum sensing

An immune signaling pathway for control of Yellow Fever Virus infection

By the Department of Molecular Biology Princeton University researchers have uncovered a critical role for a new immune signaling pathway in controlling infection by the flavivirus Yellow Fever Virus (YFV).  The paper describing this discovery was published today in the journal mBio. Infection with YFV causes a devastating illness with a mortality rate of up … Continue reading An immune signaling pathway for control of Yellow Fever Virus infection

‘Acidic patch’ regulates access to genetic information

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By Pooja Makhijani for the Department of Chemistry Chromatin remodelers — protein machines that pack and unpack chromatin, the tightly wound DNA-protein complex in cell nuclei — are essential and powerful regulators for critical cellular processes, such as replication, recombination and gene transcription and repression. In a new study published Aug. 2 in the journal Nature, … Continue reading ‘Acidic patch’ regulates access to genetic information