Genetic instructions from mom set the pattern for embryonic development

Micrograph of a zebrafish organ called the Kupffer's vesicle

By the Department of Molecular Biology A new study indicates an essential role for a maternally inherited gene in embryonic development. The study found that zebrafish that failed to inherit specific genetic instructions from mom developed fatal defects earlier in development, even if the fish could make their own version of the gene. The study … Continue reading Genetic instructions from mom set the pattern for embryonic development

Researchers’ Sudoku strategy democratizes powerful tool for genetics research (Nature Communications)

By Tien Nguyen, Department of Chemistry Researchers at Princeton and Harvard Universities have developed a way to produce the tools for figuring out gene function faster and cheaper than current methods, according to new research in the journal Nature Communications. The function of sizable chunks of many organisms’ genomes is a mystery, and figuring out … Continue reading Researchers’ Sudoku strategy democratizes powerful tool for genetics research (Nature Communications)

“Kurly” protein keeps cilia moving, oriented in the right direction (Cell Reports)

By Catherine Zandonella, Office of the Dean for Research A new study of a protein found in cilia – the hair-like projections on the cell surface – may help explain how genetic defects in cilia play a role in developmental abnormalities, kidney disease and a number of other disorders. The researchers at Princeton University and … Continue reading “Kurly” protein keeps cilia moving, oriented in the right direction (Cell Reports)